Your first bottle of L-Methylfolate is free · Ships today
All seven Clean Health Lab formulas stepped on travertine blocks against a deep sage wall in morning sun

Most vitamins come in the wrong form.

Seven formulas in the active form your body uses, at maximum strength.

The line

Shop all seven

L-Methylfolate ships today. The other six are restocking, and backorders ship first.

Not sure where to start?
TMG bottle with its cap off on travertine

TMG

1000 mg betaine

Backorder
SAM-e bottle beside a stoneware cup on travertine

SAM-e

400 mg, enteric coated

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Lab results

An outside lab tests every lot before it ships.

Lot number · L-MethylfolateHighland Laboratories 0077136
  • PotencyMeets the label
  • Heavy metalsBelow every limit
  • MicrobiologyWithin limits
  • E. coliNegative
Read the report for your lot
An L-Methylfolate bottle beside glass sample vials on a steel lab bench
Fingertips pulling one small capsule apart over travertine, its pale yellow powder spilled in raking sun

Ingredients

If pills upset you, check the fillers.

In every formula

  • Active form
  • Maximum strength
  • Vegan capsule

Left out of every one

  • Magnesium stearate
  • Silica
  • Flow agents

Why active forms

40%

of people carry a gene that slows folic acid.

Most vitamins still use folic acid anyway, so every formula here uses the active form.

How fast your body converts folic acidMethylfolate doesn't need converting

100%Ready
No variant
65%Ready
One copy
30%Ready
Two copies
  • FolateMethylfolateFolic acid
  • B-12MethylcobalaminCyanocobalamin
  • B vitaminsCoenzyme formsSynthetic forms
  • Vitamin DD3 + K2D3 alone
MTHFR enzyme speed by gene · Frosst et al., Nature Genetics, 1995

Reviews

4.9
★★★★★

from 2,600+ reviews

"I was taking supplements that I thought were helping me, but they were actually made with synthetic folic acid."

Eliza, tired with two under two, found out from blood work that she carries the MTHFR gene
Eliza holding her bottle
Tired, MTHFR gene★★★★★

"This is my second bottle, and I'm finally starting to feel like I have my energy back."

@eliza.cornelison
A customer holding her L-Methylfolate bottle
Small pill, no fillers★★★★★

"This is a teeny tiny pill. You only have to take one for the serving size. There's also no fillers."

@howgrowsit
A customer holding her L-Methylfolate box
Her night routine★★★★★

"Along with an iron supplement, I take methyl folate. I will never go back."

@momofboys40
Candace with her bottle
Energy and mood★★★★★

"I use this a lot to give me energy and help with my mood. I also like that it contains zero fillers."

@candacereviews
A customer with her first bottle

What to expect

Your first year on L-Methylfolate

  1. Day 1

    One small capsule with breakfast

  2. A few weeks in

    "The fog has lifted quite a bit."

  3. Day 60

    Twice as many people improved as on a placebo

  4. Month 12

    61% felt well again, and no one who recovered relapsed

Day 60: Papakostas et al., American Journal of Psychiatry, 2012, 15 mg a day for 60 days (32% improved vs 15% on placebo). Month 12: Zajecka et al., Journal of Clinical Psychiatry, 2016, a year on 15 mg.

See L-Methylfolate

Learn

Start here if you just got an MTHFR result.

All articles
Fingertips holding one small capsule beside the open L-Methylfolate bottle on travertine

60-day guarantee

Try any formula for 60 days.

If it isn't for you, we'll refund you, even if the bottle's open.

What bothers you most?

Start with

L-Methylfolate 15 mg

Get my first bottle free